University of California, Riverside

Southern California Eukaryotic Pathogen Symposium

Keynote Speaker 2016

Richard smRichard E. Davis, University of Colorado

"Programmed DNA Elimination in Parasitic Nematodes"

Lab Summary – The Davis Lab studies the molecular biology of parasitic worms (primarily schistosomes and parasitic nematodes) with a focus on atypical molecular processes including spliced leader RNA trans-splicing and programmed DNA elimination. Our previous studies on trans-splicing used cell-free in vitro systems, biolistic RNA transfection, enzymatic, and structural biology approaches to examine the cellular and biochemical adaptations of mRNA translation and decay to trans-splicing.  Current studies are focused on programmed DNA elimination in parasitic nematodes, a phenomenon where chromosomes break and regions of chromosomes are reproducibly lost during early development.  We use a variety of approaches to study DNA elimination including genomics and transcriptomics, biochemistry, analysis of small RNAs and Argonautes, chromatin and chromosome analyses, and analysis of chromosome segregation.

Selected Publications

See a full list of Dr. Davis' publications.

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Department Information

Division of Biological Sciences
B0600 Statistics Building

Tel: (951) 827-5705
Fax: (951) 827-3699